Mark Krikorian must be joking:

So, now worrying about Shia maniacs with nukes makes you an Iranophobe? It’s a brilliant piece of linguistic jiu jitsu designed to confuse and weaken the United States; whoever thought it up, therefore, must have studied at an American university.

I prefer the word Persophobe to describe the attitude, but I don’t think it’s a stretch to apply a term like this to people who have an exaggerated and irrational fear of a medium-sized country that poses no significant threat to the United States. Describing attitudes in terms of phobias can be overdone, and it can be used to discourage reasonable criticism, but it’s also a fairly conventional way to describe an attitude of hostility, suspicion, and distrust towards a particular nation. It was appropriate to refer to anti-French attitudes in 2002-03 as Francophobia, just as it would have been correct to describe most Americans in the 19th century as Anglophobic. The U.S. can hardly be confused and weakened by a term that correctly describes the attitude of its government towards Iran.